Extractive Spectrophotometric Method for Determination of Dipeptidyl Peptidase-4 Inhibitors in Bulk and Their Pharmaceutical Dosage Forms
نویسندگان
چکیده
Copy right © 2013 This is an Open Access article distributed under the terms of the Indo American journal of Pharmaceutical Research, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ARTICLE INFO ABSTRACT Article history Received 31/10/2013 Available online 28/11/2013
منابع مشابه
Determination of Sitagliptin Phosphate in Bulk Drugs by Extractive Spectrophotometric Method
An extractive spectrophotometric method is described for the assay of sitagliptin phosphate in bulk drug and in tablets. Sitagliptin phosphatewas extracted as an ion-pair complex from the solution containing Eriochrome black T and 0.1N HCl into chloroform and the absorbance of the complex was measured at 500nm.The working conditions of the method were investigated and optimized. Beer’s law plot...
متن کاملSpectrophotometric Determination of Tropicamide in Bulk and Pharmaceutical Formulations
A simple and sensitive extractive spectrophotometric method is described for determination of tropicamide. The method is based on the reaction of tropicamide and bromocresol green. The ion-paired colored complex was extracted with chloroform at pH 3. The extracted complex showed maximum absorbance at 423 nm. The complex was stable up to 2 days and obeyed Beer's law over the concentration r...
متن کاملSpectrophotometric Analysis of Vardenafil in Tablet Dosage Forms by Using Electrophilic Coupling Reagents
Two new spectrophotometric methods (M1 and M2) are developed for the determination of vardenafil in bulk and in tablet dosage forms. The method M1 involves oxidative coupling of vardenafil with 3-methyl-2-benzothiazolinone hydrazone hydrochloride in presence of ferric chloride in acidic medium yielding green colored chromogen with absorption maxima at 625 nm. The method M2 is based on the oxida...
متن کاملValidated Spectrophtometric Method for Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Forms
In this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at pH 3.5. The formed yellow color complex was extracted with chloroform and measured at 415 nm. The optimum reaction conditio...
متن کاملValidated Spectrophtometric Method for Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Forms
In this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at pH 3.5. The formed yellow color complex was extracted with chloroform and measured at 415 nm. The optimum reaction conditio...
متن کامل